Are schizophrenia and autism close relations?

Discussion in 'Parenting News' started by runawaybunny, Oct 23, 2012.

  1. runawaybunny

    runawaybunny Guest

    Tel Aviv University researcher discovers that family history of schizophrenia is a risk factor for autism

    Autism Spectrum Disorders (Autism Spectrum Disorders (ASD)), a category that includes autism, Asperger Syndrome, and Pervasive Developmental Disorder, are characterized by difficulty with social interaction and communication, or repetitive behaviors. The U.S. Centers for Disease Control and Management says that one in 88 children in the US is somewhere on the Autism spectrum — an alarming ten-fold increase in the last four decades.

    New research by Dr. Mark Weiser of Tel Aviv University's Sackler Faculty of Medicine and the Sheba Medical Center has revealed that Autism Spectrum Disorders (ASD) appears share a root cause with other mental illnesses, including schizophrenia and bipolar disorder. At first glance, schizophrenia and autism may look like completely different illnesses, he says. But closer inspection reveals many common traits, including social and cognitive dysfunction and a decreased ability to lead normal lives and function in the real world.

    Studying extensive databases in Israel and Sweden, the researchers discovered that the two illnesses had a genetic link, representing a heightened risk within families. They found that people who have a schizophrenic sibling are 12 times more likely to have autism than those with no schizophrenia in the family. The presence of bipolar disorder in a sibling showed a similar pattern of association, but to a lesser degree.

    A scientific leap forward, this study sheds new light on the genetics of these disorders. The results will help scientists better understand the genetics of mental illness, says Dr. Weiser, and may prove to be a fruitful direction for future research. The findings have been published in the Archives of General Psychiatry.

    All in the family

    Researchers used three data sets, one in Israel and two in Sweden, to determine the familial connection between schizophrenia and autism. The Israeli database alone, used under the auspices of the ethics committees of both the Sheba Medical Center and the Israeli Defense Forces, included anonymous information about more than a million soldiers, including patients with schizophrenia and Autism Spectrum Disorders (ASD).

    "We found the same results in all three data sets," he says, noting that the ability to replicate the findings across these extensive databases is what makes this study so significant.

    Understanding this genetic connection could be a missing link, Dr. Weiser says, and provides a fresh direction for study. The researchers are now taking this research in a clinical direction. For now, though, the findings shouldn't influence the way that doctors treat patients with either illness, he adds.

    *

    Story Source:
    The above story is reprinted from materials provided by American Friends of Tel Aviv University

    Study Reference:
    This work was done in collaboration with researchers at the University of North Carolina, Karolinska Institute in Sweden, Kings College London, and the Israeli Defense Force Medical Corps.

    Disclaimer:
    This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ConductDisorders or its staff
     
  2. JJJ

    JJJ Active Member

    It makes a lot of sense. Kanga is schitzoaffective and Eeyore has autism. Piglet even has a few Aspie tendencies. They are genetic siblings. I can see the studies eventually showing the some forms of schitzo (the ones with childhood onset) are an extreme form of autism. Kanga and Eeyore have many overlapping symptoms.
     
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