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Depression or bipolar?
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<blockquote data-quote="Sara PA" data-source="post: 14208" data-attributes="member: 1498"><p>Only Prozac has been approved for the treatment of MDD (major depressive disorder) in children and adolescents and it is the <em>only</em> one that has been shown to be effective and that's only for about 10%. (Efficacy is calculated by comparing the results for kids taking the drug to kids taking a placebo. When the placebo efficacy rate is subtracted from the drug efficacy rate, the difference is considered to be net efficacy of the drug. Prozac's is around 10%, the others are nowhere near that. There are some researchers who believe that the methodology of the Prozac studies should not be considered reliable and that it shouldn't not have been approved either.)</p><p> </p><p>Safety is separate from efficacy. ADs come with a high rate of psychiatric/central nervous system side effects, especially for children, which can occur regardless of the any conditions the child might have. </p><p></p><p>Prozac, Zoloft, Luvox, and Anafranil are approved for Obsessive Compulsive Disorder (OCD) in pediatric patients. Those not approved for the treatment of MDD are not approved because of lack of efficacy in treating MDD. </p><p></p><p>Celexa has been tested and it is not effective or safe for use by children and adolescents. The studies were not even submitted to the approval process or published because the results were so poor. If Lexapro (a close relative of Celexa) has been studied, the results are certainly not sufficiently good to gain FDA approval for it's use by children and adolescents or informaton about the studies would be circulating.</p></blockquote><p></p>
[QUOTE="Sara PA, post: 14208, member: 1498"] Only Prozac has been approved for the treatment of MDD (major depressive disorder) in children and adolescents and it is the [i]only[/i] one that has been shown to be effective and that's only for about 10%. (Efficacy is calculated by comparing the results for kids taking the drug to kids taking a placebo. When the placebo efficacy rate is subtracted from the drug efficacy rate, the difference is considered to be net efficacy of the drug. Prozac's is around 10%, the others are nowhere near that. There are some researchers who believe that the methodology of the Prozac studies should not be considered reliable and that it shouldn't not have been approved either.) Safety is separate from efficacy. ADs come with a high rate of psychiatric/central nervous system side effects, especially for children, which can occur regardless of the any conditions the child might have. Prozac, Zoloft, Luvox, and Anafranil are approved for Obsessive Compulsive Disorder (OCD) in pediatric patients. Those not approved for the treatment of MDD are not approved because of lack of efficacy in treating MDD. Celexa has been tested and it is not effective or safe for use by children and adolescents. The studies were not even submitted to the approval process or published because the results were so poor. If Lexapro (a close relative of Celexa) has been studied, the results are certainly not sufficiently good to gain FDA approval for it's use by children and adolescents or informaton about the studies would be circulating. [/QUOTE]
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