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Fast drug metabolizers?
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<blockquote data-quote="gcvmom" data-source="post: 232546" data-attributes="member: 3444"><p>Okay, found it. </p><p> </p><p>UC Irvine Pathology Services offers the CYP450 Amplichip test to determine whether you have the genotype designating what type of drug metabolizer you are!</p><p> </p><p>Here's an excerpt from their site:</p><ul> <li data-xf-list-type="ul">The majority of people are <strong>extensive metabolizers</strong> who can be administered drugs following "standard" dosing practices</li> <li data-xf-list-type="ul">Some people are <strong>intermediate metabolizers</strong>, meaning that they metabolize drugs at a slower-than-normal rate&#8212;somewhere between the rates of poor and extensive metabolizers. Multiple drug therapy regimens can turn these people into poor metabolizers because drugs can also inhibit their metabolic enzyme activity</li> <li data-xf-list-type="ul">Some people are <strong>poor metabolizers</strong> with a "deficiency" in drug metabolism, which could lead to life-threatening drug accumulation and severe adverse reactions</li> <li data-xf-list-type="ul">Some people are <strong>ultrarapid metabolizers</strong> who break down drugs at faster rates than extensive metabolizers. These people may experience either no effect or less-than-expected effectiveness from their drug therapy</li> </ul><p>The only downside is cost, of course. Most insurance plans still consider this investigational, and the cost is anywhere from $600 to $1,300. </p><p></p><p>I'll call the lab tomorrow just for yucks and see what they charge.</p></blockquote><p></p>
[QUOTE="gcvmom, post: 232546, member: 3444"] Okay, found it. UC Irvine Pathology Services offers the CYP450 Amplichip test to determine whether you have the genotype designating what type of drug metabolizer you are! Here's an excerpt from their site: [LIST] [*]The majority of people are [B]extensive metabolizers[/B] who can be administered drugs following "standard" dosing practices [*]Some people are [B]intermediate metabolizers[/B], meaning that they metabolize drugs at a slower-than-normal rate—somewhere between the rates of poor and extensive metabolizers. Multiple drug therapy regimens can turn these people into poor metabolizers because drugs can also inhibit their metabolic enzyme activity [*]Some people are [B]poor metabolizers[/B] with a "deficiency" in drug metabolism, which could lead to life-threatening drug accumulation and severe adverse reactions [*]Some people are [B]ultrarapid metabolizers[/B] who break down drugs at faster rates than extensive metabolizers. These people may experience either no effect or less-than-expected effectiveness from their drug therapy [/LIST]The only downside is cost, of course. Most insurance plans still consider this investigational, and the cost is anywhere from $600 to $1,300. I'll call the lab tomorrow just for yucks and see what they charge. [/QUOTE]
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