I have been grasping at straws the past few months and have taken difficult child to an immunologist and a chiropractor. The chiro suggested testing his hair for heavy metal output. My insurance covered it, so I said sure, what can it hurt. *** He has no mercury in his hair whatsoever. She says that indicates he may have the much debated Mercury toxicity . She said this may also be a clue about why his drug interactions can be so bizzare - that his body processes things differently, or not at all. *** The other very interesting thing from this test was his Maganese levels were off the charts. I don't have the report with me, but he had something like 400% of the "ideal" level. In researching, I found this article, which claims "Manganese rarely causes side effects when taken orally. It is possible, however, for manganese toxicity to occur in those who regularly inhale manganese vapors, such as industrial workers in steel mills and mines. Potential symptoms of such toxicity include loss of appetite, headaches, leg cramps, muscle rigidity, tremors, convulsions, extreme irritability, acts of violence, and hallucinations. Manganese toxicity has also been seen in individuals who received very high amounts of intravenous nutrition (containing manganese) administered over long periods of time." It also says "In addition, some experts believe that medications for schizophrenia and other forms of psychosis may worsen side effects from manganese supplements. Therefore, individuals taking haloperidol or other antipsychotic medications (particularly a class called phenothiazines which includes chlorpromazine, mesoridazine, perphenazine, prochlorperazine, thioridazine, and trifluoperazine) should use manganese only under the careful supervision of a qualified health professional". Obviously, he's not taking a supplement, but he's getting massive amounts of this mineral from somewhere. *** http://www.umm.edu/altmed/articles/manganese-000314.htm *** I have no idea what this means, if anything. I meet with her tomorrow without difficult child to discuss this. I then plan to take it to the immunologist, see what he says about it.