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How fast does Zoloft work?
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<blockquote data-quote="rlsnights" data-source="post: 412012" data-attributes="member: 7948"><p>The SSRI's normally take as long as several months to fully kick in.</p><p></p><p>In our/my experience what you are seeing could be one of two things.</p><p></p><p>1. Placebo effect - she knows she's taking a new medication and her brain is reacting to the idea that the medicine is helping.</p><p>2. She is really bipolar and this is the prelude to the development of a hypomanic or manic reaction provoked or brought on by the SSRI.</p><p></p><p>If it's the former you are probably right and this is a honeymoon period that will crash. But hopefully not before the medication kicks in so you may not see a huge change if what she really needed was the SSRI.</p><p></p><p>If it's the latter then you will see a shift into higher energy, less sleep (normally but not necessarily), increased grandiosity (often takes the form of defiance of authority in kids), increase in how much she talks, interrupts, changes direction, etc.</p><p></p><p>Given the family history I am afraid I would go with the 2nd possibility over the first one. I would call the psychiatrist right away if you begin seeing signs of mania developing. My difficult child 2 responded to Zoloft with hypomania/mania within about 2 weeks of starting Zoloft. It wasn't pretty but it was very helpful diagnostically. If difficult child starts to develop anything you think could be mania/hypomania I would stop the medication immediately if you haven't been able to talk to the psychiatrist yet. I am not a doctor of course but Zoloft has a 26 hour half life and skipping it for one day is really not going to make a big difference if your psychiatrist feels difficult child should stay on it.</p><p></p><p>Patricia</p></blockquote><p></p>
[QUOTE="rlsnights, post: 412012, member: 7948"] The SSRI's normally take as long as several months to fully kick in. In our/my experience what you are seeing could be one of two things. 1. Placebo effect - she knows she's taking a new medication and her brain is reacting to the idea that the medicine is helping. 2. She is really bipolar and this is the prelude to the development of a hypomanic or manic reaction provoked or brought on by the SSRI. If it's the former you are probably right and this is a honeymoon period that will crash. But hopefully not before the medication kicks in so you may not see a huge change if what she really needed was the SSRI. If it's the latter then you will see a shift into higher energy, less sleep (normally but not necessarily), increased grandiosity (often takes the form of defiance of authority in kids), increase in how much she talks, interrupts, changes direction, etc. Given the family history I am afraid I would go with the 2nd possibility over the first one. I would call the psychiatrist right away if you begin seeing signs of mania developing. My difficult child 2 responded to Zoloft with hypomania/mania within about 2 weeks of starting Zoloft. It wasn't pretty but it was very helpful diagnostically. If difficult child starts to develop anything you think could be mania/hypomania I would stop the medication immediately if you haven't been able to talk to the psychiatrist yet. I am not a doctor of course but Zoloft has a 26 hour half life and skipping it for one day is really not going to make a big difference if your psychiatrist feels difficult child should stay on it. Patricia [/QUOTE]
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