My son is on 3mg. of Intuniv. We had to gradually increase his dose to that level. It is one of the "cleanest" in terms of SE's. The only side effect we had was that my son was very sleepy when we started him on it for maybe a few weeks, and the same each time we increased the dose. After a few weeks he was completely fine with-no side effects at all. We had him on other stimulant ADHD medications and he couldn't tolerate the SE's, so that's why we tried Intuniv. It has been an excellent medication for us. He's great at school and better at home than before the medication, but he was still having issues with-ODD at home, so we recently added a low dose of Concerta. It's too soon to tell for sure, but thankfully, he's having no SE's from the Concerta with-the Intuniv and he's doing really really well.