To begin, I really want to thank all of you for your support & prayers over my health situation over the last year. At best, things have been difficult, the changes in my abilities frustrating & living in the "unknown" maddening/depressing on any given day. I appreciate your patience with my lack of response to many threads I should have been able to contribute to....but had no energy or couldn't find the words. That may continue for a while. I left the clinic with a plan! No definitive diagnosis but a plan. I spent almost 2 hours in rheumatology yesterday morning. I have Cushings Disease from being on the prednisone for so very long (10 months now). My body didn't tolerate the last titrate to discontinue this medication so we are going from a different angle. We have to "convince" my body that it doesn't need this medication anymore. In the meantime, rheum doctor is looking at the possibility of many of the autoimmune disorders, possibly - likely combined with neuro issues. Neuro doctor is going to be following the d/c of the prednisone closely & working with rheum doctor. She refuses to rule in/rule out anything at this point until the prednisone is mostly out of my system. In the meantime, there are areas of my brain on the MRI that she will be watching closely - it doesn't fit MS to a tee; neither do the lesions, scarring, or "suspect areas" fit Susac's to a tee. Neuro doctor was most concerned over my last MRI - I was unable to be aroused during & after the procedure plus there was a great deal of movement during the MRI. Apparently all the tests to arouse were tried & after the MRI was complete they brought a doctor in to help. Neuro doctor has concerns over that - not convinced it was seizure activity, not sure what it was. Neuro doctor will be studying the MRIs very closely over the next 2 or 3 weeks. And I say that because I head down to Mayo again to see rheum doctor in 2 weeks for a follow up on the d/c of prednisone. He may have some test results back to indicate what is going on with my autoimmune system; he would like to introduce a non sterodial anti autoimmune medication if it's indicated at that time. And I left the clinic yesterday with more confidence that someone had a clue - even though the doctor's still haven't a clue. Or if they do, they aren't sharing. Instead I left with a plan - get off this cruddy steroid & plan on attending my oldest neice's wedding mid May followed by the Mother's Day annual golf outing. (I may not be able to golf well - I can darned well drive the cart & have a Mike's hard lemondade in honor of my mom on the 5th hole with my sisters & SILs.) Again, thank you for all your support. Keep your fingers crossed that this plan works. I need to be well (functional) again.