I have never been to a forum before, but as my username suggests, I am at a complete loss as what to do! My son has always been Obsessive Compulsive Disorder (OCD), been athletic, and did great in school. After he hit teen years and has gone through some bad experiences, he has gotten totally apathetic. Recently, he started becoming defiant and eventually aggressive and hostile. He was diagnosed with Depression, Obsessive Compulsive Disorder (OCD) and ADHD. The Dr. prescribed Prozac which made him wildly erratic and mean. He was then diagnosed with BiPolar. They now prescribe Seorquel, which I am afraid to give him until I hear from other parents. Though apathetic for the last 2-3 years, in the last 6 months, he does not care about ANYTHING, including any consequences. He gets A's in school, if he goes. He runs away all the time. He started smoking pot (says its the ONLY time he is happy and he doesn't care if its illegal because everyone is just stupid), occassionally drinks alcohol, has taken other kids Albuterol and recently started taking huge doses of cold medicine. He throws and breaks things when he doesn't get his way and fights "below the belt". He was never "mean" before, but has always been resistent to change, stubborn, and digs his heels in. He genuinely seems remorseful when he runs away or gets bad grades. He turned F's and zero's into C's, in a week and a half. But when I found drugs on him and grounded him, it started all over again and he ran away. My concern is the diagnosis and getting him on the right drugs. Obsessive Compulsive Disorder (OCD), ODD and Depression are resolved with SSRI's, but that made him worse. ADHD medications can trigger Bipolar reaction, but we haven't tried them. THe BiPolar medications scare me to death. My gut tells me its totally Obsessive Compulsive Disorder (OCD) behavior, and then anger and remorse for not being perfect...(along with some teen manipulation and defiance) but if SSRI's don't work, what then?