Probiotic Bacteria May Lessen Anxiety And Depression Related Disorders

Discussion in 'Parenting News' started by runawaybunny, Sep 2, 2011.

  1. runawaybunny

    runawaybunny Guest

    Probiotic bacteria have the potential to alter brain neurochemistry and treat anxiety and depression-related disorders according to research published in the prestigious international journal Proceedings of the National Academy of Sciences USA.

    The research, carried out by Dr Javier Bravo and Professor John Cryan and their colleagues at the Alimentary Pharmabiotic Centre in UCC, along with collaborators from the Brain-Body Institute, McMaster University in Canada, demonstrated that mice fed with Lactobacillus rhamnosus JB-1 showed significantly fewer stress, anxiety and depression-related behaviours than those fed with just broth. Moreover, ingestion of the bacteria resulted in significantly lower levels of the stress-induced hormone, corticosterone.

    This study identifies potential brain targets and a pathway through which certain gut organisms can alter mouse brain chemistry and behaviour. These findings highlight the important role of bacteria in the bidirectional communication between the gut and the brain, the gutbrain axis and opens up intriguing opportunity of developing unique microbial-based strategies for treatment for stress-related psychiatric disorders such as anxiety and depression, said John F. Cryan, senior author on the publication and Professor of Anatomy and Principal Investigator at the Science Foundation Ireland funded Alimentary Pharmabiotic Centre, at UCC.

    The researchers also showed that regular feeding with the Lactobacillus strain caused changes in the expression of receptors for the neurotransmitter GABA in the mouse brain, which is the first time that it has been demonstrated that potential probiotics have a direct effect on brain chemistry in normal situations. The authors also established that the vagus nerve is the main relay between the microbiome (bacteria in the gut) and the brain. This three way communication system is known as the microbiome-gut-brain axis and these findings highlight the important role of bacteria in the communication between the gut and the brain, and offer the intriguing possibility that certain probiotic organisms may prove to be useful adjunct therapies in stress-related psychiatric disorders.

    Story Source:
    The above story is reprinted from materials provided by University College Cork.

    Journal Reference:
    The research is published online ahead of print in Proceedings of the National Academy of Sciences USA 29 August 2011 d.o.i.10.1073/pnas.1102999108 "Ingestion of Lactobacillus strain regulates emotional behaviour and central GABA receptor expression in a mouse via the vagus nerve" Authors: J.A. Bravo, P. Forsythe, M.V.Chew, E. Escaravage. H.M.Savignac , T.G. Dinan, J. Bienenstock & J.F.Cryan.

    This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ConductDisorders or its staff.
  2. keista

    keista New Member

    WAY COOL!!!!!!!!!!!! Now if I could only get DD1 to swallow those horse pills. Tried offering some to her when the stomach bug was infiltrating our house, but they are quite large. Maybe can find some made just for kids.
  3. shellyd67

    shellyd67 Active Member

    Please excuse my lack of knowledge here but can this be found in yogurt? I keep hearing the commercial for Activia and it contains probiotic bacteria??? I think. Gonna look it up now. difficult child loves yogurt but nothing comes this easy lol
  4. keista

    keista New Member

    Activia is BS. All yogurt has bacteria. Activia has something called "bifidus regularis". It's their own proprietary blend of bacteria and since it's top secret, nobody knows what it is. FWIW I tried Activia for a week and couldn't sleep. The day I stopped eating it I was able to sleep. ??????? But does support the mind-gut connection.

    Probiotics that you get at health food stores (the best ones require refrigeration) contain several strains of good bacteria. The one I have contains 12.
  5. HaoZi

    HaoZi Guest

    I love Activia, my system does do better on it, but it does just as well on the Fiber One and WW yogurts, too.