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Rh incompatibility issues
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<blockquote data-quote="AnnieO" data-source="post: 436279" data-attributes="member: 6705"><p>Janet,</p><p> </p><p>I am O-. Usually the Rh factor comes into play not on the <em>first</em> pregnancy, but on subsequent ones. Rh is a protein found on the surface of blood cells - and you can be O+ and Rh- at the same time (Starbie). Rh+ is by far vastly more common for <em>everyone</em>.</p><p> </p><p>This is how things work: During the first pregnancy, <em>if</em> the father is Rh+, and the mother is Rh-, the mother's body can build up antibodies against Rh+ antigens. Baby is usually fine. However, on subsequent pregnancies, the antibodies are already there - so, if the baby gets that strand of DNA from Daddy, and is Rh+, mama's body will try to kill the baby. Usually this succeeds and you have a late miscarriage. Sometimes not and you have birth defects. Women who are Rh- are urged to get the Rh immunoglobulin injection. They've learned a lot since they discovered this and now urge women who are Rh- to get the RhIg shot around week 28 of the first pregnancy - just to be safe.</p><p> </p><p>Only reason I know all this is - I am Rh- - more than 85% of people are Rh+. My Mom is, and Grandma was, Rh- as well - and Grandma lost 2 boys after Mom was born. This was before the RhIg shot was avaiable.</p><p> </p><p>...And husband is likely positive... Sigh.</p></blockquote><p></p>
[QUOTE="AnnieO, post: 436279, member: 6705"] Janet, I am O-. Usually the Rh factor comes into play not on the [I]first[/I] pregnancy, but on subsequent ones. Rh is a protein found on the surface of blood cells - and you can be O+ and Rh- at the same time (Starbie). Rh+ is by far vastly more common for [I]everyone[/I]. This is how things work: During the first pregnancy, [I]if[/I] the father is Rh+, and the mother is Rh-, the mother's body can build up antibodies against Rh+ antigens. Baby is usually fine. However, on subsequent pregnancies, the antibodies are already there - so, if the baby gets that strand of DNA from Daddy, and is Rh+, mama's body will try to kill the baby. Usually this succeeds and you have a late miscarriage. Sometimes not and you have birth defects. Women who are Rh- are urged to get the Rh immunoglobulin injection. They've learned a lot since they discovered this and now urge women who are Rh- to get the RhIg shot around week 28 of the first pregnancy - just to be safe. Only reason I know all this is - I am Rh- - more than 85% of people are Rh+. My Mom is, and Grandma was, Rh- as well - and Grandma lost 2 boys after Mom was born. This was before the RhIg shot was avaiable. ...And husband is likely positive... Sigh. [/QUOTE]
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