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Scientific Report - Extra brain cells may be key to Autism
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<blockquote data-quote="Marguerite" data-source="post: 478517" data-attributes="member: 1991"><p>I looked up a newspaper article on this - a friend emailed the link to me. I'm perusing the journal article now.</p><p></p><p>My concern with this - sample size coupled with wide age range. I think it really is too difficult to be able to say with any significance, that there is a link. There are too many other possible factors. I'd like to see their individual results before I would be prepared to comment further.</p><p></p><p>But I do think it shows a direction in future research, and surely brain imaging can show size of various parts of the brain in vivo? That would give a better sample size. Also more representative, because to only be able to study dead kids automatically biases the study towards only those kids most likely to die (sounds morbid). So what about the more high-functioning kids on the spectrum?</p><p></p><p>The next question is causality. This study implies prenatal development involvement. I do know difficult child 3 was born with an outsized head. They have been doing studies on head circumference at birth and soon after, and difficult child 3 actually does not fit the usual picture - kids on the spectrum, according to an earlier study, tend to have smaller than average head circumference at birth but then rapid early growth flips it to outsized. difficult child 3 started out outsized.</p><p></p><p>In short - this needs more careful study. And if it is shown to be true, then we need to look at how, and why. However, if it does turn out to be true then perhaps it would be a useful tool on neonatal screening, so intensive therapy can be commenced ASAP.</p><p></p><p>Marg</p></blockquote><p></p>
[QUOTE="Marguerite, post: 478517, member: 1991"] I looked up a newspaper article on this - a friend emailed the link to me. I'm perusing the journal article now. My concern with this - sample size coupled with wide age range. I think it really is too difficult to be able to say with any significance, that there is a link. There are too many other possible factors. I'd like to see their individual results before I would be prepared to comment further. But I do think it shows a direction in future research, and surely brain imaging can show size of various parts of the brain in vivo? That would give a better sample size. Also more representative, because to only be able to study dead kids automatically biases the study towards only those kids most likely to die (sounds morbid). So what about the more high-functioning kids on the spectrum? The next question is causality. This study implies prenatal development involvement. I do know difficult child 3 was born with an outsized head. They have been doing studies on head circumference at birth and soon after, and difficult child 3 actually does not fit the usual picture - kids on the spectrum, according to an earlier study, tend to have smaller than average head circumference at birth but then rapid early growth flips it to outsized. difficult child 3 started out outsized. In short - this needs more careful study. And if it is shown to be true, then we need to look at how, and why. However, if it does turn out to be true then perhaps it would be a useful tool on neonatal screening, so intensive therapy can be commenced ASAP. Marg [/QUOTE]
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Scientific Report - Extra brain cells may be key to Autism
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