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tell me about propranolol and amantadine
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<blockquote data-quote="Marguerite" data-source="post: 258618" data-attributes="member: 1991"><p>I've been on amantadine, the doctor was trying it for pain management but it was supposed to work like other antidepressants are supposed to work, for analgesia. It made me MORE depressed, about half an hour after I took it. However, so did a lot of other antidepressants so don't let my experience put you off. The fatc that it did that to m is an indication that it works like a lot of antidepressants do.</p><p></p><p>The other thing - I noticed the effect half an hour after I took it, then it would wear off (the sudden mood drop, I mean) over the next hour. The effect didn't last. I think I was taking it twice a day, with the second dose being smaller. I only noticed the depressed mood after the morning dose, which was twice the evening dose. And as I said - I just happen to be a person who cannot tolerate any antidepressants, I have weird reactions to all of them. Actually, amantadine was one of the easier ones on me, I could tolerate the depression (especially once I realised what was causing it) but it wasn't doing anything for my pain because I was unable to increase the dose to a point where it would have had enough of an effect for me.</p><p></p><p>I was also wary of taking it because it's supposed to work by increasing free dopamine and I was breastfeeding at the time. An increase in dopamine while you're breastfeeding can slow down or shut off your milk supply, that was the only likely problem. However, from the point of view of a person trying to deal with mood disorders, anything that increases free dopamine is likely to be a good thing.</p><p></p><p>I would give it a go, if the doctor thinks it's worth a try.</p><p></p><p>Marg</p></blockquote><p></p>
[QUOTE="Marguerite, post: 258618, member: 1991"] I've been on amantadine, the doctor was trying it for pain management but it was supposed to work like other antidepressants are supposed to work, for analgesia. It made me MORE depressed, about half an hour after I took it. However, so did a lot of other antidepressants so don't let my experience put you off. The fatc that it did that to m is an indication that it works like a lot of antidepressants do. The other thing - I noticed the effect half an hour after I took it, then it would wear off (the sudden mood drop, I mean) over the next hour. The effect didn't last. I think I was taking it twice a day, with the second dose being smaller. I only noticed the depressed mood after the morning dose, which was twice the evening dose. And as I said - I just happen to be a person who cannot tolerate any antidepressants, I have weird reactions to all of them. Actually, amantadine was one of the easier ones on me, I could tolerate the depression (especially once I realised what was causing it) but it wasn't doing anything for my pain because I was unable to increase the dose to a point where it would have had enough of an effect for me. I was also wary of taking it because it's supposed to work by increasing free dopamine and I was breastfeeding at the time. An increase in dopamine while you're breastfeeding can slow down or shut off your milk supply, that was the only likely problem. However, from the point of view of a person trying to deal with mood disorders, anything that increases free dopamine is likely to be a good thing. I would give it a go, if the doctor thinks it's worth a try. Marg [/QUOTE]
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