Bipolar, Schizophrenia and Autoimmune disorders

Discussion in 'General Parenting' started by rlsnights, Feb 19, 2011.

  1. rlsnights

    rlsnights New Member

    In an earlier thread, a couple people wondered out loud about bipolar and autoimmune disorders like Crohn's Disease being genetically related.

    There is a growing body of evidence that links a range of autoimmune disorders in family members and increased risk of schizophrenia and non-affective psychosis. The evidence linking bipolar disorder to autoimmune disorders in family members does not appear to be significant except for pernicious anemia.

    According to recently published research by William Eaton of Baltimore-based Johns Hopkins University and a team of researchers the only familial level of increased risk for bipolar is associated with pernicious anemia. This is based on a Swedish population-based analysis of these associations in 3.57 million people. About 70,000 cases of schizophrenia, bipolar and non-affective psychosis were identified and analyzed.

    There appears to be stronger than expected associations between bipolar and Crohn's Disease, pernicious anemia, Celiac, Guilain-Barre and autoimmune hepatitis within the same person.

    So having a family history of autoimmune disorders generally does not seem to be associated with an increased risk of bipolar disorder. But a personal history of a handful of autoimmune disorders is associated with an increased risk of bipolar.

    For a more technical summary of a recent poster session on the question of whether Bipolar is an Autoimmune Disorder see the following blog

  2. tiredmommy

    tiredmommy Site Moderator

    Thanks! Interesting stuff.
  3. susiestar

    susiestar Roll With It

    I posted a thread in the Watercooler about the supposed "insanity virus" - a virus located on our dna that may be what triggers not just schizophrenia, but also bipolar and multiple sclerosis. Animalss injected with this virus develop the symptoms shown in these disorders - human trials may start this year in Geneva, Switzerland.