Does anyone here know if there are studies or data that examine the effects blood sugar levels can have on the effectiveness of psychiatric medications? difficult child 2 has had breakthrough symptoms the past week or so, and he's telling me he's usually really hungry when this happens. Happened again this afternoon -- he's all over the place physically and mentally and telling me he's "starving". After he eats, he seems to calm down a bit (although tonight I did give him a prn because he's just so over-the-top). It can't just be my imagination. Is it that the medications don't work as well because the brain is low on fuel? I'd really like to understand this process.