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Chronic Fatigue Syndrome
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<blockquote data-quote="Marguerite" data-source="post: 15684" data-attributes="member: 1991"><p>I was wondering about tests as well. One that I recall (it was part of research at the time) was the DTH - delayed hypersensitivity skin test. A large plastic block was pressed hard onto the forearm - it inoculated the skin with a number of common antigens and three days later the test was read. </p><p></p><p>Another test (blood test) that was done was a differential analysis of T4, T8 and NK (natural killer) cells - numbers mainly. The theory at that time was that people with CFS had an immune system that was trying to crack a walnut with an atom bomb - initial contact with antigens would result in high reactivity of the immune system (T4s) and a low response of the "let's switch it all off now, job's done" T8s. The NKs were often higher as well.</p><p></p><p>Every so often repeat blood tests would be done to check the T4/T8 status. But as I said, this was part of Sydney research back in 1978. The head of t hat team retired a couple of years ago but their work continues. A good thing - from their work, many more researchers have taken on the task. Back in the late 70s there was hardly anyone researching CFS. Then it just took off in the early 80s and more info is coming out all the time.</p><p></p><p>I still would not wish this on anyone as a diagnosis. They thought husband had this at one point - husband still hasn't got a definitive diagnosis - but they won't give him this label because what often happens is tat doctors simply stop looking, and other nastier (in terms of prognosis) conditions could still be lurking undetected.</p><p></p><p>You've had some good advice so far. But one thing to remember - it's like our kids. We're all different. Whatever your eventual diagnosis the sooner you adapt the sooner you can overcome, to the best of your ability. And adapting is going to involve what works for you. We're all different.</p><p></p><p>My diagnosis used to be a variant of CFS. I was heavily involved in support networks but have taken a giant step back (hence my research knowledge is very old). However, I do a great deal more for myself than would be expected - because I've learnt how to adapt to ME. (Sorry - bad pun).</p><p></p><p>Marg</p></blockquote><p></p>
[QUOTE="Marguerite, post: 15684, member: 1991"] I was wondering about tests as well. One that I recall (it was part of research at the time) was the DTH - delayed hypersensitivity skin test. A large plastic block was pressed hard onto the forearm - it inoculated the skin with a number of common antigens and three days later the test was read. Another test (blood test) that was done was a differential analysis of T4, T8 and NK (natural killer) cells - numbers mainly. The theory at that time was that people with CFS had an immune system that was trying to crack a walnut with an atom bomb - initial contact with antigens would result in high reactivity of the immune system (T4s) and a low response of the "let's switch it all off now, job's done" T8s. The NKs were often higher as well. Every so often repeat blood tests would be done to check the T4/T8 status. But as I said, this was part of Sydney research back in 1978. The head of t hat team retired a couple of years ago but their work continues. A good thing - from their work, many more researchers have taken on the task. Back in the late 70s there was hardly anyone researching CFS. Then it just took off in the early 80s and more info is coming out all the time. I still would not wish this on anyone as a diagnosis. They thought husband had this at one point - husband still hasn't got a definitive diagnosis - but they won't give him this label because what often happens is tat doctors simply stop looking, and other nastier (in terms of prognosis) conditions could still be lurking undetected. You've had some good advice so far. But one thing to remember - it's like our kids. We're all different. Whatever your eventual diagnosis the sooner you adapt the sooner you can overcome, to the best of your ability. And adapting is going to involve what works for you. We're all different. My diagnosis used to be a variant of CFS. I was heavily involved in support networks but have taken a giant step back (hence my research knowledge is very old). However, I do a great deal more for myself than would be expected - because I've learnt how to adapt to ME. (Sorry - bad pun). Marg [/QUOTE]
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