Hi, I just wanted to post a note saying how things are going okay this week on the guanfacine. I had my doubts since this was the 2nd medication we were trying for my difficult child's hyperactivity and irritability. Strattera was the first and it only made him more violent and oppositional to the point I was fearing injury of some sort. We ended that and are now on our 2nd week of Guanfacine and its going well. I have noticed so far that he is more cooperative, polite and doesn't hardly escalate to the levels he did previously when he would get angry or frustrated. My husband and I were talking last night and he said that he actually thought this medication was helping and that he could see a difference. That was a big thing because he's been leary of trying the medications. We have both noticed a lot of positive things. difficult child is actually sitting at the table for dinner with us getting up only 1 or 2 times vs. running past the table to grab and bite and away he would go! I am very thankful for this past week. I pray that it continues to go well. I have my eyes open and am prepared for whatever happens since I've read how many times things eventually fail later in the trial of taking medication. We got a good report from his teacher in preschool this week too. So, here's to hoping. Thanks so much for all the care and support you all give on this site. It is a godsend to me and I can't imagine what I'd do if I didn't have this great place to come to and communicate with all of you. Take Care!