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<blockquote data-quote="smallworld" data-source="post: 30004" data-attributes="member: 2423"><p>Welcome! I'm glad you found us.</p><p></p><p>Multidisciplinary evaluations are generally done at university or children's hospitals. You may have to drive a distance, but it will be worth it in your case to figure out what is what. I live near NIMH in Bethesda, MD, and I understand the clinical trials there are amazing. You definitely should pursue that avenue.</p><p></p><p>My son (difficult child 1) is not so much medication resistant as he is medication reactive. What we have found helpful is to start low and go slow with every medication he tries. We also make one medication change at a time to make sure we know what each medication is doing, positive or negative. As soon as we see adverse effects (for example, dystonic reaction with Risperdal, manic reaction with Zoloft, migraines with Strattera, etc), we wean him from that medication. Some medications like Lamictal helped a lot, but he was still experiencing resididual depression. At that point, we added a very low dose of an antidepressant. Things aren't perfect, but they're far better than they were a year ago.</p><p></p><p>There is a blood test that measures liver enzymes and their response to various psychotropic medications. We are going to have difficult child undergo it as soon as we convince him that he can tolerate a blood draw (he's very anxious about all things medically invasive). The blood test is expensive, but it may be worth your while given your difficult child's reactions to medications. </p><p></p><p>What happened when your difficult child was on Lithium and Lamictal? Has he tried any other mood stabilizers? Has he ever been on a mood stabilizer with an atypical antipsychotic at the same time?</p></blockquote><p></p>
[QUOTE="smallworld, post: 30004, member: 2423"] Welcome! I'm glad you found us. Multidisciplinary evaluations are generally done at university or children's hospitals. You may have to drive a distance, but it will be worth it in your case to figure out what is what. I live near NIMH in Bethesda, MD, and I understand the clinical trials there are amazing. You definitely should pursue that avenue. My son (difficult child 1) is not so much medication resistant as he is medication reactive. What we have found helpful is to start low and go slow with every medication he tries. We also make one medication change at a time to make sure we know what each medication is doing, positive or negative. As soon as we see adverse effects (for example, dystonic reaction with Risperdal, manic reaction with Zoloft, migraines with Strattera, etc), we wean him from that medication. Some medications like Lamictal helped a lot, but he was still experiencing resididual depression. At that point, we added a very low dose of an antidepressant. Things aren't perfect, but they're far better than they were a year ago. There is a blood test that measures liver enzymes and their response to various psychotropic medications. We are going to have difficult child undergo it as soon as we convince him that he can tolerate a blood draw (he's very anxious about all things medically invasive). The blood test is expensive, but it may be worth your while given your difficult child's reactions to medications. What happened when your difficult child was on Lithium and Lamictal? Has he tried any other mood stabilizers? Has he ever been on a mood stabilizer with an atypical antipsychotic at the same time? [/QUOTE]
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