Weve been doing some medication changes for J now that school has ended. We finally got him off Depakote completely and havent seen a return of his mania (yeah!). Hes on 100 mg BID Lamictal and 5 mg Lexapro and hes still depressed. Hes lying around the house, not wanting to do anything but computer and X-Box games. He doesnt want to go anywhere (including the pool or movies or bowling) or see friends. He quit day camp after two days. We have to work very, very hard to get him to take a shower or brush his teeth. Yesterday he refused to go to his weekly appointment with his psychiatrist so I went instead. We talked about all husband and I are noticing, and the psychiatrist decided to up Js Lamictal to 150 mg BID over the next week or so. I agreed to the medication change because Lamictal at 200 mg has helped some, but not enough. Furthermore, I think its safer at this point than increasing Lexapro because J has had bad reactions to Prozac, Zoloft and Effexor XR (the latter with a hefty dose of Depakote on board). But Ive read that there is not much antidepressant effect above 200 mg. For the parents whose kids are taking Lamictal, is your child/adolescent taking more than 200 mg? Has it helped? Is it futile for us to even think about throwing more Lamictal at the problem if it may not do anything at all? Any thoughts are appreciated.