Difficult Child has been out of the hospital for three weeks. He remains sober and off his substance. He started new antidepressant which is an MAO inhibitor. This is a medication of last resort as he has only had no to partial responses to the fifty thousand other antidepressants he's been on. His ADHD symptoms are much better. He can't take stimulants because he used to abuse them. The depression remains and he says it's really really bad this time, although he manages to slog through his day, goes to work, tries to go to the gym, goes to meetings. We saw him tonight and were impressed as grooming much better and he wasn't stopping every 5 minutes for a cigarette, less restless. But the antidepressant part might take another month to kick in. MD saw him last week and increased it again. So we are going to try and see him more often during this challenging time and also have his sister and his uncle try and spend some time with him as they live near him. He sees therapist twice a week and caseworker weekly. He was going to intensive out patient every day but stopped because he developed insomnia and couldn't get out of bed. So your collective thoughts, prayers, that this new stuff will finally begin to lift the depression would be much appreciated. As for myself. I think I'm finally starting to not be as much affected by his moods anymore. I think I'm starting to become used to all this. It's like I'm becoming numb to it. Has anyone had a similar experience? Maybe I'm finally practicing Radical Acceptance?