HI My youngest has been on Zoloft for two weeks (one week at 25 mg and one week at 50 mg). His behavior has become increasingly disruptive in class and he was suspended yesterday for the second time in a week for kicking a kid hard, apparently pretty much unprovoked. He is a big physical kid somewhat obsessed with physical action. He was put on Zoloft for his perseverative behavior (difficulty letting go of things). As a gradeschooler he was not able to tolerate a stimulant for his impulsiveness but for the past year he has been on Concerta with pretty good results. Before that on Abilify, but side effects were not so great. Have tried a couple of mood stabilizers in past but didn't have any benefits. He is not bipolar we think. Pretty much ADHD and also develelopmentally immature emotionally. Has also a diagnosis of Fetal Alcohol Effects (FAE). Husband is meeting with psychiatrist today to say we want to discontinue Zoloft. Not sure why I am writing. For those of you who have seen bad reactions to SSRI how quickly did they come on? My other son had a bad reaction (they are not biologically related) but he has a profile closer to bipolar and it was pretty quick. How long would it take to clear Zoloft from system? What do you do with a kid who is not entirelly safe at school? He is suspended this week, then no school to Jan. i am scared to send him back. I don't want him to hurt anyone both for the other kid's sake but also for my son as he doesn't need juvie at this point. AARGH!