Hi, I put difficult child back on Strattera (7 weeks ago) for the 3rd time in 2 years. I need help deciding if the side effects are worth the benefit. His sleep and eating are undisturbed by this medication, this is a big deal to me as he is a great eater and decent sleeper, so I hate to mess with those things. (difficult child is on the autism spectrum, has anxiety, and shows signs of a mood disorder, as well as adhd and odd. I realize the odd/anxiety is sometimes part and parcel with spectrum diagnosis's, but it's likely more from abusive school situations in the past for him.) Anyhow, in the past we liked strattera because it seemed to calm the adhd aspect of difficult child and enabled him to focus a bit better to do some schoolwork. (think 20 min. max for a highly engaging subject while on the strattera, 5-10 off of it.) other than that, we are seeing tantrums/rages shorter in duration. The negatives of the medication are excessive irritibility. He is so crabby, all the time. I miss his humor, even if was manic during 1/2 the time. He just seems flat emotionally. Every little thing sets him off ~so while the duration of his outbursts are less, there are more outbursts. He is extremely whiny and demanding, not pretty in an almost 12 year old. He still seems to be cycling (even though he isn't diagnosis'd with-a mood disorder)-today at school he was completely non-functional. So, off medications he is hyper almost all the time, manic periodically, irritable occasionally. On medications he is irritable non-stop, and his ups and downs are still there, but not to the same extreme. I miss having him happy and funny. He seems miserable most of the time. I can up his dosage in the next week, but if I don't particularly like the effects now, is upping it going to help?