Hi ya'll. It's been a while since I've posted, a long while. Things are actually going very well for us and for our difficult child. He went to placement for 5 weeks back in May and came back a much more managable and awesome child. One of the medications that he is taking is Trileptal and he has been having trouble on it since he started in May. I'm really just looking for a little feedback from some of you. The problem is that the medication, Trileptal, reaches it's full therapuetic load in the blood stream at two weeks. Well, at two weeks he throws up for a full 24 hours with no relief. Not even a phenergen suppository works. He, of course, does not take the medication when he is "sick." Then, when he stops puking we start the medication again and the cycle continues. There are some behavioral clues to when this will happen like he becomes less frustration tolerant and generally less happy. Then after he has been "sick" he is more pleasant, more frustration tolerant, etc.... I have only found one person in the medical field who understands what is happening. Not even his psychiatrist knows why he is having this reaction. I guess my question is, is it worth it? He misses school. Our schedule is not predictable because we cannot pinpoint the next episode to the day. The other kids' scheduled activities often suffer. Etc... I have asked about another anti-convulsive but his psychiatrist hasn't been very optimistic. I'm ready to take him off of it all together. What would you do?