Is anyone familiar with arthritic nodules? I have a spot in the middle of my left thumb that sometimes you can't feel and other times is hard like a rock under my skin and it shrieks with pain. It is NOT at a joint, where I would have expected an arthritic problem, but in the very center of the pad of my left thumb. Being right-handed mostly (ambidextrous runs in my family and some things I simply am unable to do right handed, esp sports things), this thing shocks me with pain every so often. I am also getting really nasty looking knuckles. My hands looked like little old lady arthritis hands by age sixteen but now they are even creepier, in my opinion. The kids have joked that I don't need gloves to make scary witch hands for halloween, that I could even make molds of my hands and sell copies of them for Halloween. Sweet of them, isn't it? lol They do make me smile about it because those kids of mine NEVER react the way I would expect! The problems have become far more noticeable in the last four or five months. My right pinkie finger looks like there is a pea sitting under the skin at the first knuckle - some days are worse than others but I do notice that if I do not stretch my hands several times a day that the pinkie mostly but ALL the joints do NOT want to move to their full range of motion. I learned the stretches twenty plus yrs ago when I got a false diagnosis of ankylosing spondylitis and am glad I know them. If y'all have any home remedies for this stuff, or any clue why an arthritic problem would show up in the middle of my thumb and not at the joint, I would appreciate it. Current diagnosis's do NOT include the ankylosing spondylitis because though I have the gene I just don't have the squared vertebrae (doctor that diagnosis'd it put my name on someone else's xrays. We figured it out a few years later because there was a HUGE difference in the xrays that doctor did and the xrays done at the later time. No way vertebrae change shape that way - simply is impossible, plus I don't have a number of other symptoms of it. So I have fibro, psoriatic arthritis, severe Vit D deficiency and bones that are demineralizing at a terrifying rate. To this point, NONE of the DMARDS have helped at all with the arthritis - not the biologics like enbrel and humira, not the steroids which make me nastier than cobra with PMS, not the other medications that are rx'd. The docs pretty much just look confused - NOT what you want on your third opinion's face or that of the first two docs who gave the opinions! Thanks!