Iron Deficiency in ADHD children

Discussion in 'Healthful Living / Natural Treatments' started by Malika, May 16, 2011.

  1. Malika

    Malika Well-Known Member

    [FONT=verdana, arial, helvetica, sans-serif]As a footnote to my previous post, here is an abstract of one of these studies

    Iron Deficiency in Children With Attention-Deficit/Hyperactivity Disorder
    [/FONT] [FONT=verdana, arial, helvetica, sans-serif] Eric Konofal, MD, PhD; Michel Lecendreux, MD; Isabelle Arnulf, MD, PhD; Marie-Christine Mouren, MD [/FONT]

    [FONT=verdana, arial, helvetica, sans-serif] Arch Pediatr Adolesc medication. 2004;158:1113-1115. [/FONT]
    [FONT=verdana, arial, helvetica, sans-serif] ABSTRACT [/FONT]

    [FONT=verdana, arial, helvetica, sans-serif] Background Iron deficiency causes abnormal dopaminergic neurotransmission and may contribute to the physiopathology of attention-deficit/hyperactivity disorder (ADHD). [/FONT] [FONT=verdana, arial, helvetica, sans-serif]Objective To evaluate iron deficiency in children with ADHD vs iron deficiency in an age- and sex-matched control group. [/FONT]
    [FONT=verdana, arial, helvetica, sans-serif]Design Controlled group comparison study. [/FONT]
    [FONT=verdana, arial, helvetica, sans-serif]Setting Child and Adolescent Psychopathology Department in European Pediatric Hospital, Paris, France. [/FONT]
    [FONT=verdana, arial, helvetica, sans-serif]Patients Fifty-three children with ADHD aged 4 to 14 years (mean ± school district, 9.2 ± 2.2 years) and 27 controls (mean ± school district, 9.5 ± 2.8 years). [/FONT]
    [FONT=verdana, arial, helvetica, sans-serif]Main Outcome Measures Serum ferritin levels evaluating iron stores and Conners’ Parent Rating Scale scores measuring severity of ADHD symptoms have been obtained. [/FONT]
    [FONT=verdana, arial, helvetica, sans-serif]Results The mean serum ferritin levels were lower in the children with ADHD (mean ± school district, 23 ± 13 ng/mL) than in the controls (mean ± school district, 44 ± 22 ng/mL; P < .001). Serum ferritin levels were abnormal (<30 ng/mL) in 84% of children with ADHD and 18% of controls (P < .001). In addition, low serum ferritin levels were correlated with more severe general ADHD symptoms measured with Conners’ Parent Rating Scale (Pearson correlation coefficient, r = –0.34; P < .02) and greater cognitive deficits (r = –0.38; P < .01). [/FONT]
    [FONT=verdana, arial, helvetica, sans-serif]Conclusions These results suggest that low iron stores contribute to ADHD and that ADHD children may benefit from iron supplementation. [/FONT]

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