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There are some OTC mess that can cause psychosis if over taken.  My son overdosed on Benedryl (He will try anything) and became psychotic.... Ended up in the ER because we knew something was terribly wrong.... Either some weird drug or some major problem with his brain.  Turned out it was Benedryl.  He said later that it was unpleasant because he didn't get at times he was hallucinating where as on drugs such as LSD he knew that was what was happening.