First of all, my daughter took Depakote and it made her "stupid" (her word). She couldn't think or retain anything so she refused to continue taking it. It could be the Depakote causing the cognitive dulling. Secondly, do you have regular blood levels drawn for both Depakote and Lithium? My son was on both--he had draws every two weeks and I made the doctor tell me the exact number of the level. I'd done a little homework on my own and wanted to judge for myself if this was a safe level that worked. Depakote did nothing for my son. Lithibod made him lethargic. However, he isnt bipolar--that was a misdiagnosis--so maybe that's why. Lithium is the mood stabilizer with the highest success rate however, for various reasons, the levels can go up and down so you have to keep careful track of it. Depakote too.
