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General Parenting
Concerta and morning irritability?
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<blockquote data-quote="TiredSoul" data-source="post: 558515" data-attributes="member: 3930"><p>Bluenose - that is interesting since those are both methlyphenidate. I had to look it up because I have not heard of Biphentin. Here is something I read which may explain why it didn't work the same - maybe releasing less medicine at first and causing more rebound in afternoon/evening. </p><p></p><p>Biphentin is a methylphenidate drug too, but the mechanism of action is different, instead of being a ''pump'' pushing the drug during the day (OROS mechanism), is multilayers beads that melt gradually during the day . And Biphentin is 40% first layer and 60% second layer and Concerta 22% first dose and 78% second and third dose.</p><p></p><p>And this - </p><p></p><p>One final difference between Biphentin and Concerta is that Biphentin releases approximately 40% of its medicine in the early part of the day, whereas Concerta only releases 22%. This may mean that Biphentin may work better for ADD/ADHD in the morning, whereas Concerta may last a little longer into the day.</p></blockquote><p></p>
[QUOTE="TiredSoul, post: 558515, member: 3930"] Bluenose - that is interesting since those are both methlyphenidate. I had to look it up because I have not heard of Biphentin. Here is something I read which may explain why it didn't work the same - maybe releasing less medicine at first and causing more rebound in afternoon/evening. Biphentin is a methylphenidate drug too, but the mechanism of action is different, instead of being a ''pump'' pushing the drug during the day (OROS mechanism), is multilayers beads that melt gradually during the day . And Biphentin is 40% first layer and 60% second layer and Concerta 22% first dose and 78% second and third dose. And this - One final difference between Biphentin and Concerta is that Biphentin releases approximately 40% of its medicine in the early part of the day, whereas Concerta only releases 22%. This may mean that Biphentin may work better for ADD/ADHD in the morning, whereas Concerta may last a little longer into the day. [/QUOTE]
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Concerta and morning irritability?
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