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Fast drug metabolizers?
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<blockquote data-quote="gcvmom" data-source="post: 232665" data-attributes="member: 3444"><p>I forgot to mention that UCI is not the only lab that offers this test. There are several around the country. If you google Amplichip, you can read more about the test and where it's offered.</p><p> </p><p>I imagine there must be other companies that have developed a similar test -- but then again, they may be one of the first.</p><p> </p><p>There is big money in genotype testing for drug metabolites. difficult child 1 underwent something similar for the immunesuppressant he takes to control his Crohn's. And while it shows if the medication is within therapeutic levels for him, we found out the hard way that our insurance does not cover this $250 test. <img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" class="smilie smilie--sprite smilie--sprite3" alt=":(" title="Frown :(" loading="lazy" data-shortname=":(" /></p><p> </p><p>The argument for this testing is that it can save someone who is more likely to develop a toxic reaction because they are poor metabolizer. But then, the counter argument is that this is the reason doctors typically choose the slow route for titrating medication dosages -- it allows them to carefully monitor how the patient responds to the drug without pushing them into dangerous levels. The only problem for the patient is that you have to be PATIENT and wait to see how the drug will work for you. In the case of a child whose life is being affected by their disease (mental or physical) time is critical because they only have so much time for their physical growth, their psycho-social growth, and their education. </p><p> </p><p>Until the insurance industry buys off on the value of this type of designer testing, the rest of us will probably have to live with doing things the old fashioned way <img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" class="smilie smilie--sprite smilie--sprite8" alt=":D" title="Big Grin :D" loading="lazy" data-shortname=":D" /></p></blockquote><p></p>
[QUOTE="gcvmom, post: 232665, member: 3444"] I forgot to mention that UCI is not the only lab that offers this test. There are several around the country. If you google Amplichip, you can read more about the test and where it's offered. I imagine there must be other companies that have developed a similar test -- but then again, they may be one of the first. There is big money in genotype testing for drug metabolites. difficult child 1 underwent something similar for the immunesuppressant he takes to control his Crohn's. And while it shows if the medication is within therapeutic levels for him, we found out the hard way that our insurance does not cover this $250 test. :( The argument for this testing is that it can save someone who is more likely to develop a toxic reaction because they are poor metabolizer. But then, the counter argument is that this is the reason doctors typically choose the slow route for titrating medication dosages -- it allows them to carefully monitor how the patient responds to the drug without pushing them into dangerous levels. The only problem for the patient is that you have to be PATIENT and wait to see how the drug will work for you. In the case of a child whose life is being affected by their disease (mental or physical) time is critical because they only have so much time for their physical growth, their psycho-social growth, and their education. Until the insurance industry buys off on the value of this type of designer testing, the rest of us will probably have to live with doing things the old fashioned way :D [/QUOTE]
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