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We are considering switching J from 600 mg regular Seroquel to 600 mg Seroquel XR.  We currently give it to him at 9 pm, but his psychiatrist said if we switch to XR, we should be giving it between 5 and 6 pm so the sedation kicks in when he should be going to bed.  The way you're giving it now, difficult child 2's evening dose is peaking between 1:30 and 2:30 am, which might contribute to morning fatigue.  I'm wondering if you should back your evening  dose up.  But I don't know when you'd give your afternoon dose -- maybe leave it alone???


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