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General Parenting
medication question...when is it too much???
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<blockquote data-quote="smallworld" data-source="post: 88058" data-attributes="member: 2423"><p>Your difficult child's doses are on the high end. However, it does depend somewhat on how his liver metabolizes medications. How does your difficult child seem? Does he seem unusually sleepy or lethargic? Is he having any side effects that you're aware of?</p><p></p><p>Depakote is dosed by blood level -- some kids with BiPolar (BP) do well on a blood level of 80 to 90, while others require a level of 100 to 125. Higher than 125 can be toxic to the liver. Has your difficult child had a recent blood draw to determine his Depakote blood level? That would definitely help determine whether his dose is too high. When my kids were on Depakote, they never took higher than 1000 mg.</p><p></p><p>Most adolescents take up to 600 mg Seroquel a day, but I have heard of some children taking 800 mg. Is your difficult child experiencing any unsual involuntary movements or is his appetite so ravenous that he is gaining weight rapidly. Those would be two side effects to be concerned about. Cholesterol, triglycerides and glucose levels should be checked at least every six months (and should have been checked prior to beginning Seroquel). All of the atypical antipsychotics can lead to diabetes and high cholesterol.</p><p></p><p>Clonidine is a blood pressure medication. Because your son is on a high dose of Clonidine, you should have his blood pressure checked to make sure it isn't getting too low. In addition, there was a little girl in the Boston area who died of a Clonidine overdose. I don't know how much she was given, but I would be sure to ask the psychiatrists if they're concerned about your difficult child's dose.</p></blockquote><p></p>
[QUOTE="smallworld, post: 88058, member: 2423"] Your difficult child's doses are on the high end. However, it does depend somewhat on how his liver metabolizes medications. How does your difficult child seem? Does he seem unusually sleepy or lethargic? Is he having any side effects that you're aware of? Depakote is dosed by blood level -- some kids with BiPolar (BP) do well on a blood level of 80 to 90, while others require a level of 100 to 125. Higher than 125 can be toxic to the liver. Has your difficult child had a recent blood draw to determine his Depakote blood level? That would definitely help determine whether his dose is too high. When my kids were on Depakote, they never took higher than 1000 mg. Most adolescents take up to 600 mg Seroquel a day, but I have heard of some children taking 800 mg. Is your difficult child experiencing any unsual involuntary movements or is his appetite so ravenous that he is gaining weight rapidly. Those would be two side effects to be concerned about. Cholesterol, triglycerides and glucose levels should be checked at least every six months (and should have been checked prior to beginning Seroquel). All of the atypical antipsychotics can lead to diabetes and high cholesterol. Clonidine is a blood pressure medication. Because your son is on a high dose of Clonidine, you should have his blood pressure checked to make sure it isn't getting too low. In addition, there was a little girl in the Boston area who died of a Clonidine overdose. I don't know how much she was given, but I would be sure to ask the psychiatrists if they're concerned about your difficult child's dose. [/QUOTE]
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medication question...when is it too much???
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