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<blockquote data-quote="Sara PA" data-source="post: 78494" data-attributes="member: 1498"><p>The studies you read about Risperdal not lowering the seizure threshold -- was it limited to tonic-clonic seizures or did they look at partial seizure activity? I have seen anecdotal reporting of a number of children with behavioral disorders -- often Early Onset Bi-Polar (EOBP) - whose raging gets worse while taking an antipsychotic. I believe it's a red flag for the behaviors being caused by seizure activity.</p><p></p><p>The Tileptal dose is lower than the recommended dose for his weight. Initial dose is 600 mg/day; target dose for 20kg is 900 mg/day. Since Trileptal is considered (through it's similarity to Tegretol) to be a mood stabilizer, have you considered a high dose of Trileptal rather than an antipsychotic? However, I must warn you that a lot of parents report an initial worsening of behavior when Trileptal is started or increased.</p><p></p><p>Have you considered that his behavioral issues are partial seizure activity? I have links....</p><p></p><p>The Pediatric Neurology Site: Seizures</p><p><a href="http://www.childbrain.com/seizure1.shtml" target="_blank">http://www.childbrain.com/seizure1.shtml</a></p><p></p><p>MEDLINEplus Medical Encyclopedia: Seizures</p><p><a href="http://www.nlm.nih.gov/medlineplus/ency/article/003200.htm" target="_blank">http://www.nlm.nih.gov/medlineplus/ency/article/003200.htm</a></p><p></p><p>Partial (focal) seizure</p><p><a href="http://www.nlm.nih.gov/medlineplus/ency/article/000697.htm" target="_blank">http://www.nlm.nih.gov/medlineplus/ency/article/000697.htm</a></p><p></p><p>Medications which may lower seizure threshold</p><p><a href="http://www.australianprescriber.com/magazine/24/1/8/9/#" target="_blank">http://www.australianprescriber.com/magazine/24/1/8/9/#</a></p><p></p><p>Possible Temporal Lobe Symptoms</p><p><a href="http://www.pni.org/neuropsychiatry/seizures/ptls.html" target="_blank">http://www.pni.org/neuropsychiatry/seizures/ptls.html</a></p><p></p><p>Temporal lobe lesions</p><p><a href="http://www.patient.co.uk/doctor/Temporal-Lobe-Lesions.htm" target="_blank">http://www.patient.co.uk/doctor/Temporal-Lobe-Lesions.htm</a></p><p></p><p>Temporal Lobe Epilepsy</p><p><a href="http://www.patient.co.uk/doctor/Temporal-Lobe-Epilepsy.htm" target="_blank">http://www.patient.co.uk/doctor/Temporal-Lobe-Epilepsy.htm</a></p><p></p><p>Abdominal Epilepsy</p><p><a href="http://www.meridianinstitute.com/abepilep.htm" target="_blank">http://www.meridianinstitute.com/abepilep.htm</a></p><p></p><p>Fear as the main feature of epileptic seizures</p><p><a href="http://jnnp.bmjjournals.com/cgi/content/full/70/2/186" target="_blank">http://jnnp.bmjjournals.com/cgi/content/full/70/2/186</a></p><p></p><p>The Merck Manual of Diagnosis and Therapy: Seizure Disorders</p><p><a href="http://www.merckmanuals.com/professional/neurologic_disorders/seizure_disorders/seizure_disorders.html?qt=epilepsy&sc=&alt=sh" target="_blank">http://www.merckmanuals.com/professional/neurologic_disorders/seizure_disorders/seizure_disorders.html?qt=epilepsy&sc=&alt=sh</a></p></blockquote><p></p>
[QUOTE="Sara PA, post: 78494, member: 1498"] The studies you read about Risperdal not lowering the seizure threshold -- was it limited to tonic-clonic seizures or did they look at partial seizure activity? I have seen anecdotal reporting of a number of children with behavioral disorders -- often Early Onset Bi-Polar (EOBP) - whose raging gets worse while taking an antipsychotic. I believe it's a red flag for the behaviors being caused by seizure activity. The Tileptal dose is lower than the recommended dose for his weight. Initial dose is 600 mg/day; target dose for 20kg is 900 mg/day. Since Trileptal is considered (through it's similarity to Tegretol) to be a mood stabilizer, have you considered a high dose of Trileptal rather than an antipsychotic? However, I must warn you that a lot of parents report an initial worsening of behavior when Trileptal is started or increased. Have you considered that his behavioral issues are partial seizure activity? I have links.... The Pediatric Neurology Site: Seizures [URL]http://www.childbrain.com/seizure1.shtml[/URL] MEDLINEplus Medical Encyclopedia: Seizures [URL]http://www.nlm.nih.gov/medlineplus/ency/article/003200.htm[/URL] Partial (focal) seizure [URL]http://www.nlm.nih.gov/medlineplus/ency/article/000697.htm[/URL] Medications which may lower seizure threshold [URL]http://www.australianprescriber.com/magazine/24/1/8/9/#[/URL] Possible Temporal Lobe Symptoms [URL]http://www.pni.org/neuropsychiatry/seizures/ptls.html[/URL] Temporal lobe lesions [URL]http://www.patient.co.uk/doctor/Temporal-Lobe-Lesions.htm[/URL] Temporal Lobe Epilepsy [URL]http://www.patient.co.uk/doctor/Temporal-Lobe-Epilepsy.htm[/URL] Abdominal Epilepsy [URL]http://www.meridianinstitute.com/abepilep.htm[/URL] Fear as the main feature of epileptic seizures [URL]http://jnnp.bmjjournals.com/cgi/content/full/70/2/186[/URL] The Merck Manual of Diagnosis and Therapy: Seizure Disorders [URL]http://www.merckmanuals.com/professional/neurologic_disorders/seizure_disorders/seizure_disorders.html?qt=epilepsy&sc=&alt=sh[/URL] [/QUOTE]
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