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Okay, another drug question...
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<blockquote data-quote="rlsnights" data-source="post: 311066" data-attributes="member: 7948"><p>So I ran difficult child 1's medications through the drug interaction checker I use and it came back with a big red flag - class 2 drug interaction between Focalin and Amitryptaline (elavil). </p><p></p><p>It also interacts at a lower level of intensity with Daytrana and Celexa.</p><p></p><p>Looks to me like one of the big issues is that combining a tricyclic with the stimulants enhances the effects of the stimulants including increasing risk of arrhythmias, high BiPolar (BP), tachycardia.</p><p></p><p>So I would not try to combine all those again without the psychiatrist involved. Don't know why you would have this effect on his current regime since it is very similar to the previous one with the Lexapro and I'm not sure it is to blame for the ODD stuff but I would be cautious about doing it. May be that there's something different in the pharmacology interaction between Celexa and elavil vs. Lexapro and elavil that would explain it.</p><p></p><p>You could talk to your pharmacist about this too.</p><p></p><p>Finally, hate to say it, but is there any chance you're seeing a shift to some bipolar features? The one time someone put me on elavil I went into a major mixed episode.</p></blockquote><p></p>
[QUOTE="rlsnights, post: 311066, member: 7948"] So I ran difficult child 1's medications through the drug interaction checker I use and it came back with a big red flag - class 2 drug interaction between Focalin and Amitryptaline (elavil). It also interacts at a lower level of intensity with Daytrana and Celexa. Looks to me like one of the big issues is that combining a tricyclic with the stimulants enhances the effects of the stimulants including increasing risk of arrhythmias, high BiPolar (BP), tachycardia. So I would not try to combine all those again without the psychiatrist involved. Don't know why you would have this effect on his current regime since it is very similar to the previous one with the Lexapro and I'm not sure it is to blame for the ODD stuff but I would be cautious about doing it. May be that there's something different in the pharmacology interaction between Celexa and elavil vs. Lexapro and elavil that would explain it. You could talk to your pharmacist about this too. Finally, hate to say it, but is there any chance you're seeing a shift to some bipolar features? The one time someone put me on elavil I went into a major mixed episode. [/QUOTE]
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