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Seroquel and Tardive Dyskenesia
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<blockquote data-quote="gcvmom" data-source="post: 188958" data-attributes="member: 3444"><p>My difficult child 2 had an acute dystonic reaction to Zyprexa after just two doses last Spring. I didn't know what was happening so I took him to the ER. It was very frightening because I'd never seen this in anyone before. He had the torticolis with his head, the eyes were turning upward, he was drooling, his jaw was being pulled to the side (and very painfully so), he had facial grimacing, he started to make strange noises, and he complained of trouble breathing. They gave him benedryl and two shots of decadron in his butt muscle, kept him for about an hour's observation and when the symptoms had subsided, let us go.</p><p> </p><p>In hind sight, he had a much milder form of this about a year previous when he was on Abilify. Before that he had been on Risperdal with no problems to speak of.</p><p> </p><p>We decided to try Risperdal again after the Zyprexa failure, but within a day, he started back having the same kind of dystonic reaction (without the breathing problem) so we Difficult Child'd that right away!</p><p> </p><p>That said, he DOES have a low level tremor which started about two years ago. Everyone I've asked said it's NOT due to the medications (psychiatrist, AND neuro). The neuro evaluated him (physical, brain MRI, blood work) and diagnosis'd Sydenham's Chorea because he has high strep titers and because the tremor was sort of a sudden onset, and because the movements are like choreoathetosis. I'm still thinking of getting a second opinion because I'm not completely convinced it's not medication-related. Then again, when my difficult child 2 was off everything at one point, he STILL had the tremor.</p><p> </p><p>difficult child 2 has been on Seroquel XR since June (ironically, the atypical AP's are supposed to HELP the chorea/tremor) and seems to be doing better with his mood AND ADHD symptoms. But the tremor persists. psychiatrist said Seroquel works a bit differently than the AP's so he did not expect us to see any dystonic problems like before.</p><p> </p><p>That said, you know that everyone's drug experience is not the same. I hope that the medication wean resolves the symptoms your son is having.</p></blockquote><p></p>
[QUOTE="gcvmom, post: 188958, member: 3444"] My difficult child 2 had an acute dystonic reaction to Zyprexa after just two doses last Spring. I didn't know what was happening so I took him to the ER. It was very frightening because I'd never seen this in anyone before. He had the torticolis with his head, the eyes were turning upward, he was drooling, his jaw was being pulled to the side (and very painfully so), he had facial grimacing, he started to make strange noises, and he complained of trouble breathing. They gave him benedryl and two shots of decadron in his butt muscle, kept him for about an hour's observation and when the symptoms had subsided, let us go. In hind sight, he had a much milder form of this about a year previous when he was on Abilify. Before that he had been on Risperdal with no problems to speak of. We decided to try Risperdal again after the Zyprexa failure, but within a day, he started back having the same kind of dystonic reaction (without the breathing problem) so we Difficult Child'd that right away! That said, he DOES have a low level tremor which started about two years ago. Everyone I've asked said it's NOT due to the medications (psychiatrist, AND neuro). The neuro evaluated him (physical, brain MRI, blood work) and diagnosis'd Sydenham's Chorea because he has high strep titers and because the tremor was sort of a sudden onset, and because the movements are like choreoathetosis. I'm still thinking of getting a second opinion because I'm not completely convinced it's not medication-related. Then again, when my difficult child 2 was off everything at one point, he STILL had the tremor. difficult child 2 has been on Seroquel XR since June (ironically, the atypical AP's are supposed to HELP the chorea/tremor) and seems to be doing better with his mood AND ADHD symptoms. But the tremor persists. psychiatrist said Seroquel works a bit differently than the AP's so he did not expect us to see any dystonic problems like before. That said, you know that everyone's drug experience is not the same. I hope that the medication wean resolves the symptoms your son is having. [/QUOTE]
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