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General Parenting
Suicide warning to be placed on mood stabilizers
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<blockquote data-quote="Sara PA" data-source="post: 162836" data-attributes="member: 1498"><p>Depression and suiciality really aren't as connected as most people think. They are related and often found in the same person but the genetic material that controls depression isn't the same stuff that controls suicidality. Not everyone who has suicidal ideation is depressed, particularly those whose suicidal ideation is the result of an adverse reaction to a medication. Suicide can be an impulsive, <em>compulsive</em> act, unrelated to depression. </p><p></p><p>Drugs are tested using double blind studies, both on patients with the disorder being treated and on "healthy" patients. That protocol controls for the diagnosis being the cause of the reaction rather than the drug. </p><p></p><p>From the article "Overall, four people in the drug-treated groups committed suicide, and none in the placebo groups. For every 1,000 patients, about two more patients taking epilepsy drugs experienced suicidal thoughts than those who took placebo." If it were indeed the disorder and not the drug, one would expect that the suicidal ideation and acts among the placebo group would be the same as the group taking the drugs. When that's not the case, the drug is suspect. Just like outperforming the placebo indicates the drug is effective, a higher number of adverse reactions than the placebo indicates the drug is at fault.</p></blockquote><p></p>
[QUOTE="Sara PA, post: 162836, member: 1498"] Depression and suiciality really aren't as connected as most people think. They are related and often found in the same person but the genetic material that controls depression isn't the same stuff that controls suicidality. Not everyone who has suicidal ideation is depressed, particularly those whose suicidal ideation is the result of an adverse reaction to a medication. Suicide can be an impulsive, [I]compulsive[/I] act, unrelated to depression. Drugs are tested using double blind studies, both on patients with the disorder being treated and on "healthy" patients. That protocol controls for the diagnosis being the cause of the reaction rather than the drug. From the article "Overall, four people in the drug-treated groups committed suicide, and none in the placebo groups. For every 1,000 patients, about two more patients taking epilepsy drugs experienced suicidal thoughts than those who took placebo." If it were indeed the disorder and not the drug, one would expect that the suicidal ideation and acts among the placebo group would be the same as the group taking the drugs. When that's not the case, the drug is suspect. Just like outperforming the placebo indicates the drug is effective, a higher number of adverse reactions than the placebo indicates the drug is at fault. [/QUOTE]
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Suicide warning to be placed on mood stabilizers
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