Ok, understanding that I am not a doctor (and don't play one here) lol I 'll just give you a totally non-medical opinion, as a mom who has done the medication thing with myself and my son.
Pretend your kid was my kid, and this is only what *I* would do, not anyone else here: I would want him off the ADHD medication. I don't believe you can or should try to medicate away every symptom. I'm for getting the most out of a medication for less. As for the Lexipro, yes, that can cause swinging moods, if the child has a mood disorder. I would also want to slowly wean off of that (and he will get worse before better because there is a bad SSRI withdrawl syndrom). I'd want to start over and try a mood stabilizer first. And if he tends toward depression, my personal choice would be Lamictal. Then I'd take it from there, but I wouldn't like the doctor to say, "Oh, so he's got anxiety? Another pill. Oh, he's inattentive? Another pill."
I have bipolar and at one time I was on so many medications I barely knew my name anymore. I was completely zombied out. I'm sure people thought, "Wow, it's working. She's so calm" lol. That wasn't it. I felt awful and foggy and wanted to die, but I was easier to be around because I could barely react. So rather than piling medication upon medication, I would start with a mood stabilizer. For inattention I'd get school supports. Stimulants can and often do work against a mood stabilizer, as can STraterra, an antidepressant. You will NEVER get rid of every symptom, but you CAN cause your child to be emotionally dead. There is a difference between good medication that helps and too much medication that shuts down a person's ability to feel.
Anyhow, JMO