Yep.....have it. It can be a big deal SOMETIMES but usually once you get on medications and they get your levels in the normal range (between 0-4 ish) it's nothing more than taking your medications every day. It will probably take a couple of weeks before you notice a difference if not a little more. I initially lose a few pounds when I start my medications (was off for a while due to lack of insurance.) but even if you don't, you will feel so much better. It's easier to stay awake during the day, you have more energy and your brain isn't as sluggish.
When I was originally diagnosed, my level was around 67 or so. When I got tested recently once we got insurance again....it was 167. You'll have to do periodic blood tests at first (about every 6 weeks or so) until they find the right dosage for you but once you do......you only have to do it once a year unless there's a change.
I have noticed also, that a lot of people in my family have it. (mom, cousin, aunts, etc.) We're to the point now that when we all get together, if someone who doesn't have it says they have been feeling run down/tired, etc......the first the we ask is if they've been tested yet.
I'm not sure what kind of information you were looking for but hope that helps! (Oh, and be sure to take your medications on an empty stomach. It absorbs better that way)