Got2Sleep

New Member
Just spent the evening in the ER. About 6:45 pm, he came to me with drool
bubbles and his mouth at an odd angle. I thought he was choking on something.
He got his drink, and it all ran out and he was jumping up and down, not able to
close his mouth. I looked and could see nothing and his mouth was at a strange
angle.
We went to ER--his Oxygen level was like 82 so they took him directly back with
oxygen. They came in and did a breathing treatment and took x-rays of chest and
soft tissue in mouth. He was fine by this time and not really anything to see.
Within 20 minutes, it all started over. Mouth with huge drool bubbles and his
neck off to one side. The doctor(his primary care doctor was on call) came in and
tried to move his neck over, nothing. He was shaking all over, slurred speech,
tongue hanging out...and his mouth started to lock in a clenched state. This
lasted about 15 minutes and was over. After about 30 minutes, it began again.
They drew blood and his Depakote level was 102. He had 750mg at 8:20 am, and
then 250mg at 12:30 pm. We did not give any night medications tonight at all. The doctor
thought about Ativan to calm him, but I said NO WAY as it totally does the
opposite.
We are now home and just watching for any signs of breathing difficulties.
So...until then.
 

DammitJanet

Well-Known Member
Isnt this the same little boy who just increased the depakote to 2000 mgs a day?

I have no idea if depakote can do the same thing but lamictal has a very rare side effect of causing lock jaw. I know a woman who takes it and when she increased to 200 mgs a day of lamictal it started causing this locked jaw effect so she had to take a 25 mg of benedryl along with it to stop the side effect.

Now hers didnt interfere with her breathing or anything, it was just uncomfortable.

Might want to run it by a pharmacist to see if depakote can have this very rare side effect too. They are in the same class so it may be possible.
 

Got2Sleep

New Member
Well, we can only assume it was the Depakote. We live very rural and so docs here have no real knowledge of mental health medications...especially in little ones.

We are driving to see mental team on Monday(appointment Tues). We drive 6 hrs to biggest city in state for help. Usually we do tele-health but have a doctor back on team who wants to physically see him.

Thanks.
 

Got2Sleep

New Member
Yes, same child. We are now holding Depakote until we see her on Tuesday. He did have a similar reaction to Zyprexa in Nov. He also had seizures the minute lithium reached treatment level...odd medication history for sure.
 

DammitJanet

Well-Known Member
Hmmmm...have you ever asked about having him see a psychopharmacologist? It is a hard specialist to find but with a child as difficult to medicate as yours seems to be and who has had these sorts of reactions, I would ask about trying to get an appointment with one. They normally can be found at large university medical centers.
 

nlg319

New Member
I had a reaction to Seroquel. It resembled a seizure like your son's. My whole body stiffened and I had involuntary shaking and twisting of my arms and legs and my mouth open and moved involuntarily. When the "episode" ended,I made this strange noise almost like a loud sigh. It was very scary for me, I can only imagine how scary it muust have been for your son, and for you to witness.
 

busywend

Well-Known Member
I am glad you are seeing no signs of breathing difficulty. Have the other symptoms stopped? That must have given you a few more grey hairs!
 

ForeverSpring

Well-Known Member
If he had seizures on Lithium, I'd definitely want him to have an EEG. Also, I have no clue if this can happen with Seroquel, but I think all antipsychotics can cause those kinds of symptoms. My son had really scary symptoms on both Risperdal and Zyprexa.
 

branbran

New Member
Wow, that has to be scary. So sorry you are going through this. 6 hour drive, you poor thing. That's a long way to drive for mental health, what a shame. My daughter had a similar reaction to Abilify, she was drooling, her jaw began to lock and she had an unsteady gate. She took Cogentin for a while after that to counteract the side effects.

Hope everything works out for you. Good luck at the doctor on Monday, and have a safe trip. :smile:

Janet, thanks for that big word "psychopharmacologist", I've never heard of one of those. I always learn so much from this site!!!!! :smile:
 
Top