Thank you everyone. It's been a hard evening around here. Pookie is very much a big part of our family. Duckie was subdued, husband is grasping and I'm... heartbroken. I can't bear the thought of Pookie suffering or dying alone. She's secluding herself and is drinking very little and eating even less. She's breathing through her mouth (but not panting, more like her nose is blocked). She's down to about 7 pounds which is less than half of what she weighed last year. We've been lucky to have her this long: she was diagnosis'd with lymphoblastic leukemia over 5 years ago. She's done well up until the last few months with the exception of the occasional seizure.