I posted a few months ago that difficult child was started on Zoloft while inpatient at psychiatric hospital - for severe anxiety. I was glad that we were finally addressing that piece of his puzzle, but worried when several posted warnings of the downside of Zoloft causing more trouble when it was at full effect with the BiPolar (BP) component added. Well, right on schedule, at the precise moment it was predicted that the Zoloft was at full effect, the severity of difficult child's behavior came through and it was deemed that we should wean him off the Zoloft and try something else. He has been completely off the Zoloft for weeks. My question to the medication experts on the Board is this - I believe the psychiatrist will want to try Welbutrin next - probably beginning after tomorrow afternoon's appointment. Is this a good thing to try or is there something else I might suggest? And, what is the difference between the two medications? Any advice you could give would be appreciated.