As I said in a reply to another post, I have a sick puppy dog this morning. It's 9 month old Betsy. Actually, she's been acting sick since I put her dose of frontline on her two days ago. The vet picked the dose according to her wieght. She's had it before. I put it on her in the morning, by the time I got home from school in the afternoon she was acting out of character. You could see she didn't feel good. By the next day the vomiting and diarrhea started. She got sick twice, and had bms several times. But she did eat a small amount of food last night and was drinking her water fine. And perked up after eating. Even played with her toys. This morning more diarrhea with a small amount of fresh blood. No vomiting. At first I though she managed to get something out of the trash, some old food or something. Then I remembered the timing with the frontline. Then of course I think of Parvo or distemper. Betsy's had her shots. I gave them to her myself. And I know dogs can pick up viruses too. I'm trying not to panic, I'm going to give her some rice cooked in chicken broth here in just a bit and see if that helps. I still haven't been able to reach the vet at her office. Has anyone one heard of frontline making an animal have a reaction?