easy child was taking different SSRI's over the summer to try to get her Obsessive Compulsive Disorder (OCD) under control. She took Zoloft for a few weeks until she lost weight from it. Then she took fluvoxamine for probably 6 weeks until she was hyper and impulsive. Then she tried Paxil for 5 days and was starting to get hyper and angry. In between these trials, she tapered off and started the next one pretty quickly so for the whole summer, she was mostly taking something. At the same time, she was taking Amitriptyline off and on depending on what SSRI she was taking. The latest thinking is she will be on Anafranil but we are waiting to get an EEG on Tuesday and then, if it is OK, an EKG before starting it. She has started taking 1/2 of her usual dose of Amitriptyline to help her get through this time. Now, she is complaining that she is sad. She seems better now that she has started the amitriptyline again but she still complains about it and cries most nights before bed. So my question is, does anyone think this is due to SSRI withdrawal? The crying started about one week after the last dose of Paxil. Her psychiatrist says he doesn't think so because the withdrawal is specific to the medicine and she wasn't on any of them long enough. It seems to me, she was on something all summer that was adjusting her serotonin level and now she isn't. He thinks she has depression now, too. I'm not sure it matters as far as treatment, because none of the SSRI's were good for her anyway. I just hate to think of her having something else in addition to the Obsessive Compulsive Disorder (OCD). Any thoughts?