Hi all, hope everyone had a nice Mother's Day! My difficult child has been on Abilify for 2 months and we've seen such a great turn around. We've slowly increased his dose to 5mg and we may need to increase again, but we're happy with-things for now...until Friday. Friday, pre-school called and said difficult child was hot (temp most likely, but they didn't have a thermometer) and sluggish and he told the teacher his throat hurt. I went to pick him up and took him to the pediatrician and he has strep. They put him on an antibiotic called duracef. I asked the pediatrician. if he thought it would interact with-the abilify. He said he didn't know he'd check...he hasn't had any kids on abilify so he's not used to looking for problems with it. He came back and said his computer said no interactions but we should also ask the pharmacist. Pharmacist also said no known interactions. Ok, so he started the duracef (is to take it twice a day for 10 days) on Friday night and by Saturday morning we were ALMOST back to the "old" difficult child ways. He was defiant and full of rage, everything set him off and he was difficult to reason with again...he's feeling much better, so I'm wondering if the duracef is messing with the way the abilify works....anyone have any ideas or experience with this? Thanks, I appreciate it.