DNA testing for medication


Well-Known Member
Has anyone else had it done? We tried medications a couple years ago and it was a disaster. This time, they offered to do a swab DNA testing from the inside of the cheek, send it off, and a week later we had a list if medications that was suggested. There were three columns, suggested medications, use with caution, and use with extreme caution. I guess this tells what enzymes are in the patients liver, and how they metabolizes different medications. Some medications were listed as an ultra rapid metabolized, and some were slow. The only thing for her age group was Zoloft. Her sister had the same test and the only recommended one was Celexa. The things that the oldest child should not take listed all the medications she had been tried on before!

I just thought I would post this in case others are not having luck with medication. I found some good articles by googling DNA testing for medication. Ksm


Well-Known Member
It's the new thing. I went to a NAMI mtng and the guest lecturer was an MD who was really into it. By the time I went to his talk, we'd already tried 90% of what was out there. Too late for us.
Considering how many allergic reactions my son had, and how much trial and error there was, I'd be happy to go back in time and pay the $ for the test.


Active Member
We have been considering this. I heard that they do this, or something similar at the Mayo Clinic. I'm not sure if it's cheek swab but heard that it was genetic testing to match the patient with the medication that would most likely be effective.


Staff member
A few links:

How a DNA test could determine the best drug for you - http://www.besthealthmag.ca/embrace...-prevent-side-effects-from-prescription-drugs

Antidepressants that work for one person may not work for another. A new test that personalizes drug prescription could solve the problem.

Nurses turn to DNA testing to help patients being treated with psychotropic drugs - http://news.nurse.com/article/20120827/NY01/108270004

Using a person’s DNA to predict how they will react to psychotropic drugs takes some of the trial and error out of determining which drug is best for which patient.

How Genetic Testing Can Determine Which Antidepressant To Use - http://www.healthcentral.com/depression/c/4182/109819/dna-treatment

A procedure already used by several hospitals can help to determine which of a variety of antidepressant or antipsychotic medications are most likely to work or cause side effects. A psychiatric DNA test known as GeneSightRx offers the promise of providing information to doctors in such a way that can help them select or rule out medication. The procedure for the patient is simple. Their DNA is collected via a cheek swab after which genetic testing is undertaken and the results analyzed.

Advances in Pharmacogenomics Reduce Side Effects and Save Lives - http://www.psychiatrictimes.com/art...cogenomics-reduce-side-effects-and-save-lives

Psychiatrists and other physicians have long known that patients vary considerably in their responses to psychotropic medications, with some requiring much higher or lower doses than average and others failing to respond at all. Many factors, including diet, drug-drug interactions, gender, age, overall health, hepatic disease and genetic variations, can affect the availability of a drug in the body. Now, technology, clinical research and government policy are converging to create what has been called "personalized medicine." Advances in DNA testing combined with clinical studies are helping clinicians identify the best drug or dosing strategy for a particular patient.

Psychiatric pharmacogenomic testing in clinical practice - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181940/

Given the increasingly clear cost-effectiveness of genotyping, it has recently been predicted that pharmacogenomic testing will routinely be ordered to guide the selection and dosing of psychotropic medications.

Using a pharmacogenomic algorithm to guide the treatment of depression - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565829/

We concluded that a rapidly available pharmacogenomic interpretive report provided clinical guidance that was associated with improved clinical outcomes for depressed patients treated in an outpatient psychiatric clinic setting.