Has anyone's difficult child had trouble reaching theraputic level on Depakote or any other mood stabilizer? Our difficult child had tried Lithium, which did not work. He had been on Depakote 125mg 2x daily. His blood level was 60. The psychiatrist wants him at 100. We increased over a few days to 250mg 2x daily and his latest test shows a blood level of 50. psychiatrist is a little stumped. Fast metabolism? I just had a blood panel done through pediatrician's office and thyroid was fine. Any suggestions?