Acetaminophen: Teen Asthma Trigger? - WebMD Even once-a-month use of acetaminophen -- the best-known brand name is Tylenol -- may trigger asthma in teens. Teens using acetaminophen at least monthly had 2.5 times the asthma risk of nonusers. Once-a-year users had a 43% increase in asthma risk. The findings come from a study of some 323,000 13- and 14-year-olds from 50 nations by Richard W. Beasley, MD, professor of medicine at the Medical Research Institute of New Zealand in Wellington, and colleagues.