Welcome! You can find the answers to your questions about acronyms and such in the FAQ section.
I always recommend getting professional help to prescribe alternative medications for a child. You could consult an herbalist, homeopath, naturopath, etc. I also have a lot of concerns about giving potent psychiatric drugs to young children with developing brains. Have you taken your child to a psychotherapist who specializes in ADHD or considered neurofeedback? They are both effective. Does she have any dietary triggers or allergies?
Vaxa has extensive information about pregnenolone on their site:
"Pregnenolone is an all natural hormone (steroid) produced in the mitochondria of healthy adrenal glands, liver, skin, brain, testicles, ovaries and the retina of the eyes. Made from cholesterol in the body. Pregnenolone actually helps to stimulate its own synthesis, so taking an extra supplement does not interfere, but actually helps, in its own natural production. Enzymes convert pregnenolone into either progesterone of DHEA (pregnenolone is the real "mother" hormone, as it is its chemical precursor), depending on the immediate needs of the body. The need of pregnenolone increases as we grow older, or the more often we are sick. Depressed patients have been found to have abnormally low levels of pregnenolone, as well as those that suffer from rheumatoid arthritis.Pregnenolone acts on NMDA (N-methyl-D-Aspartate) receptors which directly affect learning and memory by regulating the function the synapses between the neurons. Researchers report that pregnenolone is several hundred times more potent than any memory enhancer that has been used before. Pregnenolone appears to restore normal levels of memory hormones which decline during aging. Drugs that block cholesterol formation may in fact detrimentally block pregnenolone production thus interfering with memory and other brain function. Pregnenolone seems to have the ability of repairing the enzymes in the cytochrome P-450 system which are directly responsible for converting cholesterol into pregnenolone. Pregnenolone also appears to protect against the ravages of cortisone activity, which can decrease beta cell damage. Pregnenolone also seems to protect against "addison disease" symptoms from adrenal atrophy."