It certainly did trigger me. I was originally diagnosed with depression and ADHD. When it was found that I couldn't tolerate stims, Straterra was trialed. It was not pretty. I do have ADD, but do not take medications for it as I cannot tolerate them.
Strattera was all right for Miss KT, not great, but not bad. Hubby was a mess on Strattera, even after I'd ramped him up to correct dosage (it's weight dependent). Major mood swings, deep depressions, completely illogical...I'd tracked his dosage and behaviors on a spreadsheet, and after a month of this, I went to the doctor with him, handed him a copy of the spreadsheet, and said I wanted him on another medication. Now.
Hubby took Ritalin for years, and recently felt it wasn't helping. Doctor started him on Vyvanse. So far, I'm pleased with the results.